Timothy F Murphy Selected Research

IgA-specific serine endopeptidase

11/2018	Differential distribution of IgA-protease genotypes in mucosal and invasive isolates of Haemophilus influenzae in Sweden.
1/2018	Changes in IgA Protease Expression Are Conferred by Changes in Genomes during Persistent Infection by Nontypeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease.
12/2017	Immunoglobulin A Protease Variants Facilitate Intracellular Survival in Epithelial Cells By Nontypeable Haemophilus influenzae That Persist in the Human Respiratory Tract in Chronic Obstructive Pulmonary Disease.
12/2015	Expression of IgA Proteases by Haemophilus influenzae in the Respiratory Tract of Adults With Chronic Obstructive Pulmonary Disease.
1/2011	A clonal group of nontypeable Haemophilus influenzae with two IgA proteases is adapted to infection in chronic obstructive pulmonary disease.

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Timothy F Murphy Research Topics

Disease

36	Chronic Obstructive Pulmonary Disease (COPD) 11/2019 - 01/2002
29	Infections 12/2019 - 03/2003
15	Otitis Media 01/2018 - 04/2005
7	Respiratory Tract Infections (Respiratory Tract Infection) 11/2018 - 04/2005
6	Inflammation (Inflammations) 01/2011 - 01/2002
4	Otitis 12/2020 - 04/2013
3	Asymptomatic Infections 01/2017 - 07/2005
2	Pneumonia (Pneumonitis) 04/2009 - 12/2008
1	COVID-19 01/2022
1	Convalescence 01/2019
1	Persistent Infection 01/2018
1	Chronic Pain 01/2017
1	Otitis Media with Effusion 06/2012
1	Bacterial Infections (Bacterial Infection) 09/2011
1	Wounds and Injuries (Trauma) 12/2010
1	Hemolysis 10/2010
1	Respiratory Insufficiency (Respiratory Failure) 01/2009
1	Pneumococcal Pneumonia 12/2008
1	Leukocytosis (Pleocytosis) 12/2008
1	Lung Diseases (Lung Disease) 09/2006
1	Hypersensitivity (Allergy) 09/2006
1	Reinfection 07/2006
1	Chronic Bronchitis 12/2004
1	Virus Diseases (Viral Diseases) 06/2003

Drug/Important Bio-Agent (IBA)

23	VaccinesIBA 01/2019 - 03/2003
12	AntibodiesIBA 01/2019 - 03/2003
12	AntigensIBA 01/2018 - 03/2003
10	Proteins (Proteins, Gene)FDA Link 12/2020 - 03/2003
10	Membrane Proteins (Integral Membrane Proteins)IBA 09/2017 - 03/2003
8	Immunoglobulin A (IgA)IBA 01/2018 - 07/2005
7	Peptide Hydrolases (Proteases)FDA Link 12/2019 - 11/2009
7	Immunoglobulin G (IgG)IBA 01/2017 - 03/2003
7	EpitopesIBA 10/2009 - 03/2003
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2016 - 09/2006
5	IgA-specific serine endopeptidaseIBA 11/2018 - 01/2011
5	EnzymesIBA 01/2012 - 03/2003
4	ImmunosorbentsIBA 04/2008 - 03/2003
3	MethyltransferasesIBA 11/2019 - 01/2012
2	OligopeptidesIBA 01/2018 - 01/2017
2	Membrane Transport Proteins (Biological Pump)IBA 01/2018 - 01/2017
2	Hemagglutinins (Hemagglutinin)IBA 01/2017 - 05/2009
2	FluoroquinolonesIBA 01/2016 - 01/2002
2	MacrolidesIBA 01/2016 - 01/2002
2	Conjugate VaccinesIBA 04/2013 - 01/2009
2	Surface Antigens (Surface Antigen)IBA 06/2012 - 06/2005
2	UreaseIBA 01/2012 - 08/2011
2	Lipoproteins (Lipoprotein)IBA 01/2011 - 06/2006
1	SuspensionsIBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 07/2019
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2018
1	Virulence Factors (Pathogenicity Factors)IBA 01/2018
1	Lysosomal-Associated Membrane Protein 1IBA 12/2017
1	CationsIBA 09/2017
1	4-(2-oxapentadeca-4-yne)phenylpropanoic acidIBA 01/2017
1	Indicators and Reagents (Reagents)IBA 01/2017
1	Fimbriae Proteins (Pilin)IBA 01/2017
1	Buprenorphine (Subutex)FDA LinkGeneric 01/2017
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2016
1	Oxidoreductases (Dehydrogenase)IBA 01/2012
1	TitaniumIBA 01/2012
1	Adenosine Monophosphate (AMP)IBA 09/2011
1	Antimicrobial PeptidesIBA 09/2011
1	AcidsIBA 08/2011
1	Complement System Proteins (Complement)IBA 01/2011
1	OligosaccharidesIBA 01/2011
1	AgarIBA 10/2010
1	AntioxidantsIBA 06/2010
1	Protease Inhibitors (Protease Inhibitor)IBA 11/2009
1	Immunoglobulin D (IgD)IBA 05/2009
1	Carrier Proteins (Binding Protein)IBA 05/2009
1	Amino Acids FDA Link 05/2009
1	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2009
1	SmokeIBA 04/2009
1	Immunologic Factors (Immunomodulators)IBA 10/2008
1	Recombinant ProteinsIBA 04/2008
1	EndotoxinsIBA 06/2006
1	Peptidoglycan (Murein)IBA 06/2006
1	Bacterial AntigensIBA 06/2006
1	GlutaredoxinsIBA 04/2005
1	PeroxiredoxinsIBA 04/2005
1	MucinsIBA 11/2004
1	Peptides (Polypeptides)IBA 03/2003
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2002
1	Doxycycline (Periostat)FDA LinkGeneric 01/2002
1	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2002
1	Amoxicillin (Wymox)FDA LinkGeneric 01/2002

Therapy/Procedure

8	Therapeutics 01/2011 - 01/2002
1	Patient Readmission 01/2018
1	Artificial Respiration (Mechanical Ventilation) 03/2009